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OGDH SUBUNIT E2 MAB 100 UG

 
包装: 100 UG
运保温度: 4° C
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描述:

Details
Tested species reactivity Human
Host / Isotype Mouse / IgG1
Class Monoclonal
Type Antibody
Clone 9F4BD5
Immunogen Purified OGDH from porcine heart, purified GLUD from bovine liver.
Conjugate Unconjugated
Form Liquid
Concentration 1 mg/ml
Purification purified
Storage buffer HEPES buffered saline
Contains 0.02% sodium azide
Storage Conditions 4° C
Tested Applications Dilution *
ELISA (ELISA) Assay Dependent
Immunocytochemistry (ICC) 1.0 ug/ml
Western Blot (WB) 0.25 ug/ml

* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.

 

Background/Target Information

This gene encodes one subunit of the 2-oxoglutarate dehydrogenase complex. This complex catalyzes the overall conversion of 2-oxoglutarate (alpha-ketoglutarate) to succinyl-CoA and CO(2) during the Krebs cycle. The protein is located in the mitocondrial matrix and uses thiamine pyrophosphate as a cofactor. A congential deficiency in 2-oxoglutarate dehydrogenase activity is believed to lead to hypotonia, metabolic acidosis, and hyperlactatemia.

 


注意事项:

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
 


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