Biotin-14-dCTP is a patented dCTP analog with biotin attached at the N 4 -position of the pyrimidine base by a 14-atom linker. This nucleotide can be efficiently incorporated into DNA by nick translation in the presence of dATP, dGTP, and dTTP (1), or labeling DNA with terminal deoxynucleotide transferase (2) or random primers synthesis (3). The amount of material provided is sufficient for labeling up to 50 µg of DNA.

Performance and Quality Testing: Purity is evaluated by reverse-phase HPLC.