Reacts with the human ε-chain, a 20-kDa subunit of CD3/T cell antigen receptor complex found on 70%-80% of normal human peripheral blood lymphocytes and 60%-85% of thymocytes. Studies from the HLDA Workshop show this antibody to be mitogenic when used in conjunction with pokeweed mitogen. CD3 plays a role in signal transduction during antigen recognition. UCHT1 antibody stains intracellular CD3 unlike the other CD3 clone, HIT3a, which stains only the extracellular CD3.
原厂资料:
注意事项:
1.Since applications vary, each investigator should titrate the reagent to obtain optimal results.
2.Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before
discarding to avoid accumulation of potentially explosive deposits in plumbing.
3.Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.