CD117-APC, mouse 60 tests

Clone 3C1 recognizes mouse CD117, a 145 kDa cell surface glycoprotein belonging to the class III receptor tyrosine kinase family. CD117 is also known as c-kit and stem cell factor (SCF) receptor. It is expressed on the majority of hematopoietic progenitor cells including multipotent hematopoietic stem cells as well as some committed myeloid, erythroid and lymphoid precursor cells, and mature mast cells. CD117⁺ stem cells from murine bone marrow could also be differentiated into smooth muscle cells, myocytes, and endothelial cells in vivo.^1,2

Clone 3C1 recognizes mouse CD117, a 145 kDa cell surface glycoprotein belonging to the class III receptor tyrosine kinase family. CD117 is also known as c-kit and stem cell factor (SCF) receptor. It is expressed on the majority of hematopoietic progenitor cells including multipotent hematopoietic stem cells as well as some committed myeloid, erythroid and lymphoid precursor cells, and mature mast cells. CD117⁺ stem cells from murine bone marrow could also be differentiated into smooth muscle cells, myocytes, and endothelial cells in vivo.^1,2