A combination of mouse and rat monoclonal antibodies purified from mouse ascites or hybridoma culture supernatant. Purified by affinity chromatography using Protein A or Protein G Sepharose. These antibodies are bound in bispecific Tetrameric Antibody Complexes (TAC), which are directed against CD45RA and dextran. The subclass of the mouse monoclonal antibody is IgG1. CD45RA is an isoform of the leukocyte common antigen. It is expressed on naïve T lymphocytes and antigen density decreases upon in vitro activation. CD45RA is also expressed on most B cells, NK cells and monocytes.
Species Reactivity:
Human
Product Type:
Antibodies
Recommended For:
Depletion of human CD45RA+ naïve T cells from human peripheral blood mononuclear cell samples by combining CD45RA TAC with StemSep™ or EasySep™ magnetic cell separation
Components:
N/A
Contains:
Equipment Required:
N/A
Area of Interest:
Immunology
Cell Type:
T cells
Popular Product Line:
StemSep™
Intended Use Statement:
FOR RESEARCH USE ONLY. NOT INTENDED FOR HUMAN OR ANIMAL DIAGNOSTIC OR THERAPEUTIC USES.
ISO Statement:
STEMCELL TECHNOLOGIES INC.’S QUALITY MANAGEMENT SYSTEM IS CERTIFIED TO ISO 13485 MEDICAL DEVICE STANDARDS.
注意事项：
Hazards Identification
Emergency Overview: This product is a potential irritant to eyes, respiratory system, and skin. This product may also be harmful if ingested. Complete toxicological properties have yet to be determined.
Routes of Exposure: Absorbed through skin, eye contact, inhalation, and ingestion.
Potential Health Effects:
Eye: May cause eye irritation.
Skin: May cause skin irritation.
Inhalation: May be harmful if inhaled. Material may be irritating to mucous membranes and upper respiratory tract.
Ingestion: May be harmful if swallowed.
Chronic Effects/Carcinogenicity: Not Available
OSHA Regulatory Status: Not Available
First Aid Measures
Eyes: In case of contact with eyes, flush thoroughly with water. Call a physician.
Skin: In case of contact with skin, wash the affected area with soap and copious amounts of water. Should irritation occur, contact a physician.
Ingestion: If swallowed, wash out mouth with water provided person is conscious. Call a physician.
Inhalation: If inhaled, remove person to fresh air. If breathing becomes difficult, call a physician.
Puncture Wounds: Wash thoroughly with soap and water. Allow to bleed freely. Call a physician
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