Interferon gamma inducible protein (IP-10), also known as CXCL 10, is an 8.5kD chemokine which is expressed in a variety of murine tissues including liver, kidney, gut, thymus and spleen in response to interferon gamma.
IP-10 acts as a chemoattractant for monocytes, NK cells and certain T-cells. It is thought NK cells have an anti-tumour effect for several types of cancer and may play a role in the repair and regeneration of hepatic tissue.
Target Species
Mouse
Product Form
Purified recombinant protein - lyophilised
Preparation
Recombinant protein expressed in E.Coli
Preservative Stabilisers
None present
Protein Molecular Weight
8.5kD (77 amino acid sequence)
Reconstitution
Reconstitute with 25 ul distilled water
Purity
>98% by SDS page and HPLC analysis
Approx. Protein Concentrations
1.0 mg/ml
Note
Care should be taken during reconstitution as the protein may appear as a film at the bottom of the vial. Serotec recommend that the vial is gently mixed after reconstitution.