Hu/NHP CD152 PE BNI3 50Tst

产品编号：BD-557301 品牌：BD-Pharmingen 原厂货号：557301
产品分类：抗体 > 一抗 > 染料标记抗体
应用分类：

包装：

50Tst

运保温度:

Store undiluted at 4°C

到货周期：

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描述：

Reacts with the "cytolytic T lymphocyte-associated antigen", CTLA-4. CTLA-4 is transiently expressed on activated CD28+ T cells and binds

to CD80 and CD86 present on antigen presenting cells (APC) with high avidity. This interaction appears to deliver a negative regulatory

signal to the T cell. There are recent reports that indicate that CTLA-4 is also expressed on B cells when cultured with activated T cells,

suggesting a possible role of CTLA-4 in the regulation of B-cell response. Immobilized BNI3.1 enhances T-cell proliferation induced by CD3

and CD28.

Recent studies have showed that CD152 can be expressed by regulatory T (Treg) cells. It has been found this antibody can stain the

intracellular CD152 on the Treg cells after fixation and permeabilization of cells.

注意事项：

1.This reagent has been pre-diluted for use at the recommended Volume per Test. We typically use 1 X 10e6 cells in a 100-μl experimental sample (a test).

2.Since applications vary, each investigator should titrate the reagent to obtain optimal results.

3.Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.

4.Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

5.The antibody was conjugated with R-PE under optimum conditions, and unconjugated antibody and free PE were removed.