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MOUSE ANTI-BMI-1100 UG

 
包装: 100 UG
运保温度: -20°C
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描述:

 

Details
Tested species reactivity Human
Host / Isotype Mouse / IgG1, kappa
Class Monoclonal
Type Antibody
Clone 1H6B10G7
Immunogen Synthetic peptide derived from the mid region of the human Bim-1 protein.
Conjugate Unconjugated
Form Liquid
Concentration 0.5 mg/ml
Purification Protein A
Storage buffer PBS, pH 7.4
Preservative 0.1% sodium azide
Storage Conditions -20°C
Tested Applications Dilution *
ELISA (ELISA) Assay Dependent
Western Blot (WB) Assay Dependent

* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.

 

Background/Target Information

Component of the Polycomb group (PcG) multiprotein PRC1 complex, a complex required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. In the PRC1 complex, it is required to stimulate the E3 ubiquitin-protein ligase activity of RNF2/RING2.

 


注意事项:

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
 


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