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MS X C/EBP BETA100 UG

 
包装: 100 UG
运保温度: -20°C
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描述:

 

Details
Tested species reactivity Mouse
Host / Isotype Mouse / IgG1
Class Monoclonal
Type Antibody
Clone 18F8
Immunogen Peptide corresponding to amino acid residues from the N-terminal region of mouse C/EBP b protein
Conjugate Unconjugated
Form Liquid
Concentration 0.5 mg/ml
Purification Protein A
Storage buffer PBS, pH 7.4
Preservative 0.1% sodium azide
Storage Conditions -20°C
Tested Applications Dilution *
Immunofluorescence (IF) 5 ug/ml
Western Blot (WB) 2 ug/ml

* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.

 

Background/Target Information

The protein encoded by this intronless gene is a bZIP transcription factor which can bind as a homodimer to certain DNA regulatory regions. It can also form heterodimers with the related proteins CEBP-alpha, CEBP-delta, and CEBP-gamma. The encoded protein is important in the regulation of genes involved in immune and inflammatory responses and has been shown to bind to the IL-1 response element in the IL-6 gene, as well as to regulatory regions of several acute-phase and cytokine genes. In addition, the encoded protein can bind the promoter and upstream element and stimulate the expression of the collagen type I gene. Tissue specificity: Expressed at low levels in the lung, kidney and spleen.

 


注意事项:

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
 


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