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DRD3 ANTIBODY100 UG

 
包装: 100 UG
运保温度: -20°C
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描述:

 

Details
Tested species reactivity Human , Rat , Primate
Published species reactivity Rat
Host / Isotype Mouse / IgG3
Class Monoclonal
Type Antibody
Clone 3A8
Immunogen Fusion protein incorporating amino acid residues 252-284 of the putative third cytoplasmic loop of the human D3 receptor.
Conjugate Unconjugated
Form Liquid
Concentration 0.5 mg/ml
Purification Protein A
Storage buffer PBS, pH 7.4
Preservative 0.1% sodium azide
Storage Conditions -20°C
Tested Applications Dilution *
ELISA (ELISA) 0.1-1.0 ug/ml
Immunohistochemistry (IHC) 1-5 ug/ml
Immunoprecipitation (IP) 2-5 ug
Western Blot (WB) 1-2 ug/ml

* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.

Published Applications  
Immunohistochemistry (IHC) See 1 publications below

Background/Target Information

This gene encodes the D3 subtype of the five (D1-D5) dopamine receptors. The activity of the D3 subtype receptor is mediated by G proteins which inhibit adenylyl cyclase. This receptor is localized to the limbic areas of the brain, which are associated with cognitive, emotional, and endocrine functions. Genetic variation in this gene may be associated with susceptibility to hereditary essential tremor 1. Alternative splicing of this gene results in transcript variants encoding different isoforms, although some variants may be subject to nonsense-mediated decay (NMD). [provided by RefSeq, Jul 2008]

 


注意事项:

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
 


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