Clone REA751 recognizes the human claudin-3 antigen, an integral membrane protein which is a component of the claudin family of epithelial tight junction proteins. Claudin-3 is involved in tight junction-specific obliteration of the intercellular space. It is a low-affinity receptor for
Clostridium perfringens
enterotoxinin (CPE). Binding of CPE to claudin-3 induces epithelial cell lysis.
Additional information: Clone REA751 displays negligible binding to Fc receptors.
Alternative Names
CPE-R 2, hRVP1, CLDN3, C7orf1, CPETR2
原厂资料:
Clone REA751 recognizes the human claudin-3 antigen, an integral membrane protein which is a component of the claudin family of epithelial tight junction proteins. Claudin-3 is involved in tight junction-specific obliteration of the intercellular space. It is a low-affinity receptor for
Clostridium perfringens
enterotoxinin (CPE). Binding of CPE to claudin-3 induces epithelial cell lysis.
Additional information: Clone REA751 displays negligible binding to Fc receptors.