Purified from mouse ascites fluids by affinity chromatography
Guaranteed Application *
WB, IHC, IF
Suggested Dilutions
WB 1:200 - 1:1000, IHC 1:150,
Background
This gene encodes a member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands. The protein encoded by this gene is broadly distributed throughout the endocytic system via a tyrosine-based motif in the cytoplasmic tail. Alternatively spliced transcript variants of this gene have been observed, but their full-length nature is not known. [provided by RefSeq, Jul
Related Pathway
Hematopoietic cell lineage
原厂资料：
Gene Name
Homo sapiens CD1c molecule (CD1C)
Synonyms:
BDCA1; CD1; CD1A; R7
Immunogen
Full length human recombinant protein of human CD1C(NP_001756) produced in HEK293T cell.
Purified from mouse ascites fluids by affinity chromatography
Guaranteed Application *
WB, IHC, IF
Suggested Dilutions
WB 1:200 - 1:1000, IHC 1:150,
Background
This gene encodes a member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands. The protein encoded by this gene is broadly distributed throughout the endocytic system via a tyrosine-based motif in the cytoplasmic tail. Alternatively spliced transcript variants of this gene have been observed, but their full-length nature is not known. [provided by RefSeq, Jul
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