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Anti-CD20 (C-term) (Rabbit Monoclonal IgG)

  • 产品编号:merck-m-04-455      品牌:millipore       原厂货号:04-455
  • 产品分类:抗体 > 一抗 > 蛋白特异性一抗
  • 应用分类:
 
包装:
运保温度: -20°C
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描述:

Key Spec Table

 

Species Reactivity Key Applications Host Format Antibody Type
M, H WB, IP Rb Purified Monoclonal Antibody

Description 
Catalogue Number 04-455
Brand Family Upstate 
Trade Name
  • Upstate
Description Anti-CD20 (CT) Antibody, rabbit monoclonal

Product Information 
Format Purified
Presentation In 60% storage buffer (50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 0.01% sodium azide and 0.05% BSA) and 40% glycerol.

Applications 
Application Please note that this product will not be available for sale after March 15, 2015. Please select one of the other antibodies against this target. Anti-CD20 (C-term) Antibody, Rabbit detects level of CD20 (C-term) & has been published & validated for use in IP, WB, IH(P).
Key Applications
  • Western Blotting
  • Immunoprecipitation

Biological Information 
Immunogen KLH-conjugated synthetic peptide composed of residues at the C-terminus of human CD20.
Host Rabbit
Specificity Recognizes a region composed of residues at the C-terminus of human CD20.
Isotype IgG
Species Reactivity Mouse Human
Antibody Type Monoclonal Antibody
Entrez Gene Number
Entrez Gene Summary This gene encodes a member of the membrane-spanning 4A gene family. Members of this nascent protein family are characterized by common structural features and similar intron/exon splice boundaries and display unique expression patterns among hematopoietic cells and nonlymphoid tissues. This gene encodes a B-lymphocyte surface molecule which plays a role in the development and differentiation of B-cells into plasma cells. This family member is localized to 11q12, among a cluster of family members. Alternative splicing of this gene results in two transcript variants which encode the same protein.
Gene Symbol
  • MGC3969
  • MS4A1
  • LEU-16
  • B1
  • MS4A2
  • Leu-16
  • CD20
  • Bp35
  • S7
UniProt Number
UniProt Summary FUNCTION: SwissProt: P11836 # This protein may be involved in the regulation of B-cell activation and proliferation.
SIZE: 297 amino acids; 33077 Da 
SUBCELLULAR LOCATION: Membrane; Multi-pass membrane protein.
TISSUE SPECIFICITY: Expressed on B-cells.
PTM: Phosphorylated. Might be functionally regulated by protein kinase(s).
SIMILARITY: SwissProt: P11836 ## Belongs to the MS4A family.

Product Usage Statements 
Quality Assurance Routinely evaluated by immunoblot.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Storage and Shipping Information 
Storage Conditions 2 years at -20°C from date of shipment. Upon first thaw, and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance. Note: Variability in freezer temperatures below -20°C may cause glycerol-containing solutions to become frozen during storage.

Packaging Information 
Material Size 100 µL

 


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