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anti-Rap1GAP, rb mono

  • 产品编号:merck-m-04-413      品牌:merck-millipore       原厂货号:04-413
  • 产品分类:抗体 > 一抗 > 蛋白特异性一抗
  • 应用分类:
 
包装: EA
运保温度: -20°C
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描述:

Key Spec Table

 

Species Reactivity Key Applications Host Format Antibody Type
R, H, M IH(P), FC, IF, IP, WB Rb Purified Monoclonal Antibody

Description 
Catalogue Number 04-413
Brand Family Upstate 
Trade Name
  • Upstate
Description Anti-Rap1GAP Antibody, rabbit monoclonal
Alternate Names
  • rap1GAPII
  • RAP1 GTPase activating protein
  • RAP1GA1

Product Information 
Format Purified
Presentation 100 μL of rabbit monoclonal IgG in 30 mM Tris-Glycine (pH 7.4), 0.09 M NaCl, 0.006% sodium azide, 0.03% BSA and 40% glycerol.

Applications 
Application Anti-Rap1GAP Antibody, rabbit is an antibody against Rap1GAP for use in FC, IF, IP, WB, IH(P).
Key Applications
  • Immunohistochemistry (Paraffin)
  • Flow Cytometry
  • Immunofluorescence
  • Immunoprecipitation
  • Western Blotting
Application Notes Suggested Dilutions: 
Immunoblot Analysis: 1:50,000 
Immunoprecipitation: 1:60 
Flow Cytometry: 1:50 
Immunohistochemistry (PE): 1:100 - 1:250 
Immunfluorescence Staining: 1:100 - 1:250

Biological Information 
Immunogen KLH-conjugated synthetic peptide corresponding to the region N-terminus of the GoLoco motif of human Rap1GAP.
Host Rabbit
Specificity Recognizes the domain N-terminal to the GoLoco motif of Rap1GAP.
Isotype IgG
Species Reactivity Rat Human Mouse
Antibody Type Monoclonal Antibody
Entrez Gene Number
Gene Symbol
  • rap1GAPII
  • RAP1GAP
  • KIAA0474
  • RAP1GA1
  • Rap1GAP
UniProt Number
UniProt Summary FUNCTION: SwissProt: P47736 # GTPase activator for the nuclear Ras-related regulatory protein RAP-1A (KREV-1), converting it to the putatively inactive GDP-bound state.
SIZE: 663 amino acids; 73391 Da 
SUBCELLULAR LOCATION: Golgi apparatus membrane; Peripheral membrane protein.
TISSUE SPECIFICITY: Significant expression seen in the brain, kidney and pancreas. Abundant in the cerebral cortex and expressed at much lower levels in the spinal cord. Not detected in the lymphoid tissues.
SIMILARITY: SwissProt: P47736 ## Contains 1 GoLoco domain. & Contains 1 Rap-GAP domain.

Product Usage Statements 
Quality Assurance Routinely evaluated by immunoblot.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Storage and Shipping Information 
Storage Conditions 2 years at -20°C from date of shipment. Upon first thaw, and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance. Note: Variability in freezer temperatures below -20°C may cause glycerol-containing solutions to become frozen during storage.

Packaging Information 
Material Size 100 µL

 


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