Human PSGL-1/CD162 MAb (Clone CHO131) (500 UG)

产品编号：RD-MAB996 品牌：R&D 原厂货号：MAB996
产品分类：抗体 > 一抗 > 蛋白特异性一抗
应用分类：

包装：

运保温度:

到货周期：

登录后查看

标准价：

￥客户可见

会员价：

￥客户可见

积分：

客户可见分

登录之后可加入购物车购买，请您

运费与支付说明：

1.含干冰类产品有运费；

2. 必须现金付款或有信用额度的会员才可以直接发货，否则需要等待现金付款信息。

描述：

Molecule Information: PSGL-1/CD162

Long Name: P-Selectin Glycoprotein Ligand 1

Aliases: CD162; SELPLG

Entrez Gene IDs: 6404 (Human); 20345 (Mouse); 363930 (Rat)

Background: PSGL-1
PSGL-1 (P-Selectin Glycoprotein Ligand 1) is type I transmembrane receptor found on the surface of neutrophils, monocytes, and most lymphocytes. It is expressed as a dimeric mucin-like glycoprotein that is N-glycosylated and contains both sialylated and fucosylated O-linked oligosaccharides. PSGL-1 binds to P-, E- and L-Selectins. The calcium-dependent high affinity interaction with P-, E-, and L-Selectin mediates the tethering and rolling of neutrophils, monocytes, and/or lymphocytes on endothelial cells.

原厂资料：

Specificity:Detects human PSGL‑1/CD162. Recognizes sLe^x-bearing core 2 O‑glycan stuctures. It does not recognize sLe^x on an extended core 1 O‑glycan. The sLe^x-bearing, core 2 O‑glycan structure decorates the P-Selectin ligand PSGL-1, and the presence of this glycan structure is required for high affinity P-Selectin binding (1). This antibody stains human and canine leukocytes but does not recognize monkey, mouse, rabbit, porcine, feline or bovine leukocytes.