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描述:
Galectin-3 binding protein (Galectin-3BP), also known as MAC-2 binding protein (MAC-2BP
or M2BP), and the 90 kDa tumor associated antigen (TAA90K or 90K), is a secreted glycoprotein
of the scavenger receptor cysteinerich (SRCR) superfamily. Galectin-3BP binds Galectin-3
(formerly MAC-2) with high affinity, but also binds Galectins -1 and -7, several collagen types,
fibronectin, β1 integrins and nidogen. It is widely expressed in all extracellular fluids and in
pericellular areas of cell-rich tissues.
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