GM-CSF (granulocyte-macrophage colony-stimulating factor) is a haematopoietic growth factor which exists in both glycosylated and non-glycosylated biologically active forms, and stimulates the development of granulocytes, macrophages, early megakaryocytes and eosinophil progenitor cells. The ability of recombinant GM-CSF to increase haematopoietic cell recovery has become a focus area in the therapeutic treatment of patients following bone marrow transplantation.
Target Species
Mouse
Product Form
Purified recombinant protein - lyophilised
Preparation
Purified recombinant GM-CSF expressed in E. coli
Preservative Stabilisers
None present
Protein Molecular Weight
14.2kDa (124 amino acid residues)
Reconstitution
Reconstitute with 0.2ml distilled water.
Care should be taken during reconstitution as the protein may appear as a film at the bottom of the vial. AbD Serotec recommend that the vial is gently mixed after reconstitution.
Purity
>98% by SDS PAGE and HPLC analysis
Activity
The ED50 as determined by the dose-dependent stimulation of the proliferation of murine FDC-P1 cells is = 0.05 ng/ml, corresponding to a specific activity of = 2 x 107 units/mg.
京公网安备11010802025653 版权所有：北京逸优科技有限公司
