RANTES (regulated upon activation, normal T cell expressed and secreted), otherwise known as CCL5, is a 68 amino acid CC- chemokine which acts as a chemoattractant for monocytes, CD4+/CD45RO+ memory T cells, basophils and eosinophils, thorough binding to chemokine (C-C motif) receptor 1 (CCR1), CCR3 and CCR5.
Target Species
Human
Product Form
Purified recombinant protein - lyophilised
Preparation
Purified recombinant RANTES expressed in E. coli.
Preservative Stabilisers
None present
Protein Molecular Weight
7.8kD (68 Amino acid sequence)
Reconstitution
Reconstitute with 0.2ml distilled water
Care should be taken during reconstitution as the protein may appear as a film at the bottom of the vial. AbD Serotec recommend that the vial is gently mixed after reconstitution.
Purity
>98% by SDS PAGE
Approx. Protein Concentrations
Total protein concentration 0.1mg/ml after reconstitution