These plateable cryopreserved human hepatocytes are inducible and suitable for use in experiments monitoring in vitro enzyme induction.
Cells per vial: 4-8 million
The potentials of known clinically relevant enzyme inducers represented by 3-methylcholanthrene (3-MC, a prototypical CYP1A enzyme inducer, 3 µM), phenobarbital (PB, a prototypical CYP2B inducer, 1000 µM) and rifampicin (RIF, a prototypical CYP3A enzyme inducer, 10 µM) have been assessed to verify that each lot is inducible.
Get the Results You Need with GIBCO Hepatocytes High quality hepatocytes, with high viabilities, in vivo-like enzyme expression levels, and proper cell morphology increase the ability to draw in vitro/in vivo correlations and make sound decisions regarding a compound's fate. Experienced technicians and proprietary isolation techniques combined with stringent release specifications ensure you receive the highest quality cryopreserved hepatocytes.
Each lot is tested for: • Phase I and II enzyme activities • Proper morphology • Viabilities generally >75% • Attachment efficiency • Monolayer formation and integrity
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注意事项：
For research use only. Not intended for human or animal therapeutic or diagnostic use.
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