Symplekin Pure 25/Symplekin 50ug

产品编号：BD-610644 品牌：BD-Pharmingen 原厂货号：610644
产品分类：抗体 > 一抗 > 蛋白特异性一抗
应用分类：

包装：

运保温度:

Store undiluted at -20°C.

到货周期：

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描述：

Tight junctions or zonula occludens, are specialized epithelial cell-cell contact sites that modulate the diffusion of macromolecules and ions

through the intracellular space. Tight juctions are formed by the weaving of protein strands between two adjacent plasma membranes.

Symplekin is a protein component of the submembraneous face of the tight junctions in polar epithelial cells, but is absent in vascular

endothelium. Symplekin mRNA encodes a protein of 1142 amino acids with an apparent molecular weight of 150 kDa. Studies have shown

that both symplekin mRNA and protein are present in the cytoplasm and nucleus in a variety of cells. However, Symplekin is recruited to the

zonula occludens only in those cells which form functional cell-cell contacts.

注意事项：

1.Since applications vary, each investigator should titrate the reagent to obtain optimal results.

2.Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.