Hsp70 is a member of the heat shock or stress-induced genes whose expression is regulated at both transcriptional and translational levels.
Elevated temperatures induce a transient resistance to subsequent heat exposure in various types of cells. Although Hsp70 protein is
constitutively expressed at low levels, its expression abundantly increases in response to heat stress. During such stress, Hsp70 leaves the
cytoplasm and nucleoplasm and rapidly accumulates in the nucleolus. Removal of the stress results in the redistribution of Hsp70 to its
original locations.
原厂资料:
注意事项:
1.Since applications vary, each investigator should titrate the reagent to obtain optimal results.
2.Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.