LRP Pure 42/LRP 50ug

产品编号：BD-610512 品牌：BD-Pharmingen 原厂货号：610512
产品分类：抗体 > 一抗 > 蛋白特异性一抗
应用分类：

包装：

50ug

运保温度:

Store undiluted at -20°C.

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描述：

Drugs that selectively attack dividing cells are often used in cancer therapy. However, small cell populations do not die, but develop resistance

to a variety of toxic drugs. Multidrug resistance is achieved by gene amplification of specific membrane-bound transport ATPases that shuttle

the drugs out of cells. Some multidrug-resistant cancer cells express a protein of 110 kDa named LRP (Lung Resistance-related Protein). LRP

expression might be an indicator of prognosis after chemotherapy in acute myeloid leukemia and ovarian carcinoma. The LRP gene encodes a

protein of 896 amino acids with significant homology to the major vault protein from Dictyostelium discoideum. Although ubiquitously

expressed, LRP is most abundant in epithelial cells.

注意事项：

1.Since applications vary, each investigator should titrate the reagent to obtain optimal results.

2.Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.