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IP3R-3 Pure 2/IP3R-3 150ug

  • 产品编号:BD-610313      品牌:BD-Pharmingen       原厂货号:610313
  • 产品分类:抗体 > 一抗 > 蛋白特异性一抗
  • 应用分类:
 
包装: 150ug
运保温度: Store undiluted at -20°C .
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描述:

Inositol 1,4,5-triphosphate (IP3) functions as a second messenger for many hormones, growth factors, and neurotransmitters. IP3 causes the
release of Ca2+ from intracellular stores by binding specific receptors that are coupled to Ca2+ channels. A number of studies have identified
a family of at least four IP3 receptors (IP3R). The type III receptor (IP3R-3) has been isolated and characterized in human and rat. IP3
receptors are commonly localized in the endoplasmic reticulum, but have also been identified in the nucleus and the plasma membrane.
Co-expression of different IP3 receptors is detected in most tissues and cell lines. Although these receptors appear to have a similar specificity
for inositol phosphates, the different receptors have been reported to have different affinities for IP3 as follows: type II > type I > type III.
This antibody is routinely tested by western blot analysis. Other applications were tested at BD Biosciences Pharmingen during antibody

development only or reported in the literature.


注意事项:

1.Since applications vary, each investigator should titrate the reagent to obtain optimal results.
2.Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing. .
3.Store undiluted at -20°C .


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