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Hu CD49F PE-CF594 GOH3 25Tst

  • 产品编号:BD-562493      品牌:BD-Pharmingen       原厂货号:562493
  • 产品分类:抗体 > 一抗 > 染料标记抗体
  • 应用分类:
 
包装: 25Tst
运保温度: Store undiluted at 4°C
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描述:

The GoH3 monoclonal antibody specifically binds to CD49f or integrin α6 chain, a 150 kDa transmembrane protein, member of extracellular
matrix and cell adhesion receptor family. α6 associates with integrin β1 chain (CD29) to form VLA-6 and with integrin β4 chain (CD104) to
form the α6 β4 complex, also known as the laminin and kalinin receptor. CD49f is expressed mainly on T cells, monocytes, platelets, epithelial
and endothelial cells, perineural cells and trophoblasts of placenta. GoH3 recognizes an extracellular epitope of integrin α6 on human, mouse
and bovine cells. GoH3 has been reported to block the binding of integrin α6 to laminin P1 and E8 fragments.
This antibody is conjugated to BD Horizon™ PE-CF594, which has been developed exclusively by BD Biosciences as a better alternative to
PE-Texas Red®. PE-CF594 excites and emits at similar wavelengths to PE-Texas Red® yet exhibits improved brightness and spectral
characteristics. Due to PE having maximal absorption peaks at 496 nm and 564 nm, PE-CF594 can be excited by the blue (488-nm), green
(532-nm) and yellow-green (561-nm) lasers and can be detected with the same filter set as PE-Texas Red® (eg 610/20-nm filter).


注意事项:


1.This reagent has been pre-diluted for use at the recommended Volume per Test. We typically use 1 × 10^6 cells in a 100-μl experimental
sample (a test).
2.Since applications vary, each investigator should titrate the reagent to obtain optimal results.
3.Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
 


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