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Hu CD64 PE 10.1 25Tst

  • 产品编号:BD-561926      品牌:BD-Pharmingen       原厂货号:561926
  • 产品分类:抗体 > 一抗 > 染料标记抗体
  • 应用分类:
 
包装: 25Tst
运保温度: Store undiluted at 4°C
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描述:

The 10.1 monoclonal antibody specifically binds to CD64, a 75 kDa type I transmembrane glycoprotein that is a high affinity receptor for
human IgG (FcγRI), especially the IgG1 and IgG3 subclasses. CD64 is expressed on monocytes, macrophages, dendritic cells, granulocytes
activated with interferon-gamma and early myeloid lineage cells. CD64 associates with a signaling FcRγ homodimer to form the functional
high affinity FcγRI complex. CD64 functions in both innate and adaptive immune responses and mediates endocytosis, phagocytosis,
antibody-dependent cellular toxicity, cytokine release and superoxide generation.
 


注意事项:


1.This reagent has been pre-diluted for use at the recommended Volume per Test. We typically use 1 X 10e6 cells in a 100-μl experimental sample (a test).
2.Since applications vary, each investigator should titrate the reagent to obtain optimal results.
3.Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.
4.Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
5.The antibody was conjugated with R-PE under optimum conditions, and unconjugated antibody and free PE were removed.
 


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