Hu CD184 PE 12G5 25Tst

产品编号：BD-561733 品牌：BD-Pharmingen 原厂货号：561733
产品分类：抗体 > 一抗 > 染料标记抗体
应用分类：

包装：

25Tst

运保温度:

Store undiluted at 4°C

到货周期：

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描述：

The 12G5 monoclonal antibody specifically binds to CD184, also known as CXCR4 and Fusin. CD184/CXCR4 is a seven-transmembrane
domain, G-protein-linked, glycoprotein chemokine receptor. CD184 serves as a receptor for the C-X-C chemokine, SDF-1. It is expressed on a
wide variety of hematopietic cells, vascular endothelial cells and cells of the nervous system. CD184 plays a variety of roles in hematopoiesis,
vascularization and neural development. CD184 also functions as a coreceptor for infection with T-cell tropic strains of HIV-1 and as a
receptor for CD4-independent infection by some HIV isolates. The 12G5 antibody has been reported to block CD4-independent infection by
HIV-2 and CD4-dependent infection by some T-cell tropic isolates of HIV-1.

注意事项：

1.This reagent has been pre-diluted for use at the recommended Volume per Test. We typically use 1 X 10e6 cells in a 100-μl experimental sample (a test).
2.Since applications vary, each investigator should titrate the reagent to obtain optimal results.
3.Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.
4.Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
5.The antibody was conjugated with R-PE under optimum conditions, and unconjugated antibody and free PE were removed.