Hu Regulatory T Cell Cktl 50Tst

• 产品编号：BD-560249      品牌：BD-Pharmingen       原厂货号：560249
• 产品分类：抗体 > 一抗 > 复合抗体试剂盒
• 应用分类：

描述：

The Human Regulatory T cell cocktail is a three color reagent used to identify the natural T regulatory cell (nTreg) population. An expression
pattern of CD4+CD25int/brightCD127dim closely correlates to the expression of the transcription factor Forkhead box P3 (FoxP3). FoxP3 is
considered a specific marker to T regulatory cells (Tregs). The SK3 antibody recognizes CD4, an antigen expressed primarily on
helper/inducer T lymphocytes, although this antigen is also present in low density on monocytes. The 2A3 antibody recognizes CD25, an
antigen also known as the human low-affinity interleukin-2 receptor (IL-2R). The CD25 antigen is present on a subset of peripheral blood
lymphocytes. Antigen density increases on phytohemagglutinin (PHA)-, concanavalin A (Con A)-, and CD3-activated T lymphocytes; T
lymphocytes from mixed lymphocyte cultures; and human T-lymphocyte leukemia virus (HTLV)-infected T-lymphocyte leukemia lines.
hIL-7R-M21 reacts with the 60 - 90 kDa glycoprotein, CD127. CD127 is also known as the IL-7 receptor alpha (IL-7Rα). The receptor is a
heterodimer composed of the CD127 and the common gamma chain, shared by other cytokine receptors (IL-2R, IL-4R, IL-9R, and IL-15R).
CD127 is expressed on thymocytes, T- and B-cell progenitors, mature T cells, and some lymphoid and myeloid cells.

原厂资料：

注意事项：

1.This reagent has been pre-diluted for use at the recommended Volume per Test. We typically use 1 × 10^6 cells in a 100-μl experimental
sample (a test).
2.Since applications vary, each investigator should titrate the reagent to obtain optimal results..
3.Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before
discarding to avoid accumulation of potentially explosive deposits in plumbing.
4.Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.