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WIP (pS488) Alexa 647 K32-824 50Tst

  • 产品编号:BD-558674      品牌:BD-Pharmingen       原厂货号:558674
  • 产品分类:抗体 > 一抗 > 染料标记抗体
  • 应用分类:
 
包装: 50Tst
运保温度: tore undiluted at 4°C
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描述:

Wiskott-Adrich syndrome protein (WASP)-Interacting Protein (WIP) is a member of the verprolin family of proteins that regulate cytoskeletal
organization in a wide variety of cellular activities, including endocytosis, cellular adhesion and migration, mast cell degranulation, and
lymphocyte activation. The 503-amino acid WIP protein contains binding sites for actin (globular and filamentous) and other proteins that are
involved in the regulation of actin polymerization, such as WASP, N-WASP, profilin, cortactin, Hck, and NCK. As its functions imply, WIP
is localized in actin-rich cell structures.
The K32-824 monoclonal antibody recognizes the phosphorylated serine 488 (pS488) of human WIP. The orthologous phosphorylation sites
in mouse and rat WIP are S478 and S472, respectively.


注意事项:

 

1.This reagent has been pre-diluted for use at the recommended Volume per Test. We typically use 1 × 10^6 cells in a 100-μl experimental
sample (a test).
2.Since applications vary, each investigator should titrate the reagent to obtain optimal results.
3.Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.


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