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Bta-Tubulin Alexa 555 5H1 100Tst

  • 产品编号:BD-558608      品牌:BD-Pharmingen       原厂货号:558608
  • 产品分类:抗体 > 一抗 > 染料标记抗体
  • 应用分类:
 
包装: 100Tst
运保温度: Store undiluted at 4°C
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描述:

Tubulin is a highly conserved protein with a molecular weight of ~50 kD. The self-assembly of tubulin leads to microtubules, hollow cylinders that are one of the major components of the eukaryotic cytoskeleton. Microtubules play key roles in chromosome segregation in mitosis, intracellular transport, ciliary and flagellar bending, and structural support of the cytoskeleton. There are two main classes of tubulin isoforms, α- and β-tubulin, which are usually products of separate genes. Microtubules are made from protofilaments, strings of alternating α- and β-tubulin spaced 4 nm apart and pointing in the same direction. Tubulin can be posttranslationally modified in several ways, including phosphorylation, acetylation, glutamylation, and detyrosination. For example, microtubules that turn over slowly tend to be acetylated and detyrosinated.


注意事项:

1.Since applications vary, each investigator should titrate the reagent to obtain optimal results. 2.Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing. 3.Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.


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