Ms CD64a/b Alexa 647 X54-5/7.1 100ug

• 产品编号：BD-558539      品牌：BD-Pharmingen       原厂货号：558539
• 产品分类：抗体 > 一抗 > 染料标记抗体
• 应用分类：

描述：

The monoclonal alloantibody X54-5/7.1 reacts with FcγRI (CD64) encoded by the more common Fcgr1a and Fcgr1b alleles. The alloantigens
generated by the Fcgr1a and Fcgr1b alleles, have been confirmed positive in mouse strains BALB/c and C57BL/6 and reported positive in
strains 129, A, AKR, ALR, BUB, C3H, C57BL/10, C57BLKS, C57BR, C58, CBA, CE, DBA/2, HRS, MRL, NON, NZB, NZO, NZW, PL,
SJL, ST, SWR. The a and b alloantigens have been reported negative in mouse strains ABH, NOD. CD64, a key receptor in the development
of immune responses, has a dual role as a low affinity receptor for IgG3 and high affinity receptor for IgG2a linking innate and adaptive
immunities. CD64 mediates endocytosis, phagocytosis, antibody-dependent cellular toxicity, cytokine release and superoxide generation.
CD64 is expressed largely on macrophages and dendritic cells. For more information regarding clone X54-5/7.1 and the alloantigens it
recognizes, please refer to the reference by Tan et al listed below.

原厂资料：

注意事项：

1.Since applications vary, each investigator should titrate the reagent to obtain optimal results.

2.Store undiluted at 4°C.