Ezrin (pT567) Pure J37-954.281.307 100ug

• 产品编号：BD-558357      品牌：BD-Pharmingen       原厂货号：558357
• 产品分类：抗体 > 一抗 > 磷酸化抗体
• 应用分类：

描述：

Ezrin is a member of the ERM (Ezrin-Radixin-Moesin) family of proteins that can function as a crosslinker between the actin cytoskeleton and
the plasma membrane of the cell. Phosphorylation of threonine residues (Thr567 on Ezrin, Thr564 on Radixin and Thr558 on Moesin) has
been reported to occur with stimulation of growth factors and is important for cytoskeletal rearrangements. Phosphorylation of Thr567 at the
C-terminal F actin-binding domain has been reported to activate the conversion of Ezrin from a dormant soluble form in the cytosol to a
membrane- and actin-binding conformation.
In addition to its reactivity to the human species, the peptide used to generate this antibody is either identical or has homology to analogous
regions of mouse and rat Ezrin, Radixin and Moesin. The J37-954.281.307 monoclonal antibody has been reported to recognize
phosphorylated T567 on active Ezrin in addition to crossreacting on phosphorylated T564 on Radixin and phosphorylated T558 on Moesin.

原厂资料：

注意事项：

1.Since applications vary, each investigator should titrate the reagent to obtain optimal results.

2.Store undiluted at 4°C.