Hu DCIR Alexa 647 I3-612 100Tst

产品编号：BD-558220 品牌：BD-Pharmingen 原厂货号：558220
产品分类：抗体 > 一抗 > 染料标记抗体
应用分类：

包装：

100Tst

运保温度:

Store undiluted at 4°C

到货周期：

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描述：

The I3-612 antibody reacts with DCIR, or dendritic cell immunoreceptor, a newly identified member of the calcium-dependent (C-type) lectin family. DCIR is a type II membrane glycoprotein with a single carbohydrate recognition domain (CRD). Its cytoplasmic tail contains a consensus immunoreceptor tyrosine-based inhibitory motif (ITIM). It is expressed on monocytes, macrophages, B-lymphocytes, granulocytes, but not on NK or T cells. DCIR is strongly expressed on dendritic cells derived from peripheral blood monocytes cultured in presence of GM-CSF and IL-4. Down-regulation is observed on these with further maturation using TNF-a or LPS. Reports describe the detection of two distinct inhibitory signals depending on its ITIM tyrosine residue

注意事项：

1.This reagent has been pre-diluted for use at the recommended Volume per Test. We typically use 1 × 10^6 cells in a 100-μl experimental

sample (a test).

2.Since applications vary, each investigator should titrate the reagent to obtain optimal results..

3.Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before

discarding to avoid accumulation of potentially explosive deposits in plumbing.

4.Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.