Hu CD273 PE MIH18 100Tst

产品编号：BD-558066 品牌：BD-Pharmingen 原厂货号：558066
产品分类：抗体 > 一抗 > 染料标记抗体
应用分类：

包装：

100Tst

运保温度:

Store undiluted at 4°C

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描述：

The MIH18 monoclonal antibody specifically binds to CD273, the Programmed Death Ligand 2 (PD-L2). PD-L1 and PD-L2 are newly
discovered members of the B7 family that are the ligands for the Programmed Death 1 (PD-1) receptor. They are expressed on immature
dendritic cells and mature dendritic cells. PD-L1 is expressed on antigen-presenting cells, including IFN-g-stimulated monocytes and
activated human and mouse dendritic cells. Monoclonal antibodies that block PD- 1 and PD-L2 on dendritic cells result in enhanced T cell
proliferation and cytokine production. PD-L2, also called B7-DC, is expressed on placental trophoblasts, myocardial endothelium and
medullary thymic epithelial cells. Studies show overlapping functions of PD-L1 and PD-L2 and indicate an important role for the PD-L:PD-1
pathway in regulating T cell responses.

注意事项：

1.This reagent has been pre-diluted for use at the recommended Volume per Test. We typically use 1 X 10e6 cells in a 100-μl experimental sample (a test).
2.Since applications vary, each investigator should titrate the reagent to obtain optimal results.
3.Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.
4.Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
5.The antibody was conjugated with R-PE under optimum conditions, and unconjugated antibody and free PE were removed.