Ms Dendritic Cells PE 33D1 200ug

产品编号：BD-557578 品牌：BD-Pharmingen 原厂货号：557578
产品分类：抗体 > 一抗 > 染料标记抗体
应用分类：

包装：

200ug

运保温度:

Store undiluted at 4°C

到货周期：

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描述：

The 33D1 antibody reacts with an antigen on most dendritic cells (DC) of spleen, lymph node, and Peyer's patch, but not liver, bone marrow,

or epidermal dendritic cells; macrophages; other leukocytes; or erythroid cells. Within the spleen, the majority of 33D1+ DC are localized in

the marginal zones. Thymic dendritic cells may express a low level of the 33D1 antigen. It has been reported that bone-marrow DC can be

induced to express the 33D1 antigen by culture in the presence of GM-CSF, and the resulting 33D1+ DC are effective in in vitro (induction of

MLR) and in vivo (anti-tumoral vaccination) assays for antigen presentation. However, the addition of IL-4 to GM-CSF in bone-marrow

cultures resulted in loss of 33D1 expression and enhanced the MLR-stimulatory activity of the DC. It has also been reported that 33D1

expression is upregulated when liver-derived DC are cultured on collagen-coated plates in the presence of GM-CSF. In vivo functional 33D1+

DC are induced in the brains of mice chronically infected with Toxoplasma gondii, probably via the parasite's induction of GM-CSF.

注意事项：

1.Since applications vary, each investigator should titrate the reagent to obtain optimal results.

2.Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.

3.Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

4.The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.

5.The antibody was conjugated with R-PE under optimum conditions, and unconjugated antibody and free PE were removed.