Hu CD95 Pure G254-274 100ug

包装：

100ug

运保温度:

Store undiluted at 4°C.

到货周期：

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描述：

Programmed cell death (apoptosis) may be induced in response to a variety of cytotoxic stimuli, including activation of surface receptors. An

area of particular interest has been the induction of apoptosis by the receptor-ligand pair: Fas (CD95) and Fas Ligand (FasL). Fas is an ~45 kD

cell surface protein which belongs to the the TNF (tumor necrosis factor receptor family, and is expressed in various tissue and cells including

the thymus, liver, ovary and lung. FasL, a member of the TNF ligand family, is expressed on activated T and NK cells. FasL initiates signaling

at the cell surface by aggregation of individual Fas recpetors via binding to the multivalent ligand. Antibodies which selectively activate Fas

can be used in vitro to mimic the apoptotic response associated with FasL. Both Fas and FasL are thought to play an important role in the

apoptotic processes that take place during T cell development. Clone G254-274 recognizes human Fas. A soluble form of recombinant human

Fas (lacking the Fas transmembrane domain) was used as immunogen.

注意事项：

1.Since applications vary, each investigator should titrate the reagent to obtain optimal results.

2.Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before

discarding to avoid accumulation of potentially explosive deposits in plumbing.

3.Store undiluted at 4°C.