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Hu MUC2 Pure CCP58 100ug

  • 产品编号:BD-555926      品牌:BD-Pharmingen       原厂货号:555926
  • 产品分类:抗体 > 一抗 > 蛋白特异性一抗
  • 应用分类:
 
包装: 100ug
运保温度: Store undiluted at 4°C.
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描述:

Reacts with the core peptide of the MUC2 protein, a member of a family of mucin glycoproteins that are characterized by high carbohydrate
content, O-linked oligosaccharides, high molecular weight (>200 kD) and an amino acid composition rich in serine, threonin, proline and
glycine. The core protein contains a domain of 23 amino-acid tandem repeats which function as multiple epitopes for the monoclonal
antibody. Incomplete glycosylation of some tumor-associated mucins may lead to variable unmasking of the multiple peptide epitopes leading
to the observed differences in staining intensity between normal and malignant tissues. This antibody has been shown to be relatively tissue
specific, being associated predominantly with intestinal tissue and is highly reactive with colon and gastric tumors. The antibody is suitable for
staining formalin-fixed, paraffin-embedded tissue sections following citrate pretreatment.


注意事项:

1.Since applications vary, each investigator should titrate the reagent to obtain optimal results.
2.Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before
discarding to avoid accumulation of potentially explosive deposits in plumbing.
3.Store undiluted at 4°C.


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