Hu CD86 FITC 2331(FUN-1) 100Tst

产品编号：BD-555657 品牌：BD-Pharmingen 原厂货号：555657
产品分类：抗体 > 一抗 > 染料标记抗体
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包装：

100Tst

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描述：

增殖细胞核抗原（PCNA）最初鉴定为增殖的细胞中存在的一种细胞核抗原，随后被描述为DNA聚合酶δ的一个亚基。PCNA蛋白的水平在细胞周期的S期达到峰值，此时PCNA蛋白与p21的抑制剂形成一种复合物。PCNA在细胞周期的的其它阶段几乎检测不到。由于其独特的表达方式，PCNA已被广泛应用于肿瘤发展和肿瘤增殖的预后的相关研究。有报道指出，人PCNA由262个氨基酸组成，表观分子量为36 kDa。

原厂资料：

The Proliferating Cell Nuclear Antigen (PCNA) was initially identified as a nuclear antigen in proliferating cells and was subsequently described as a subunit for DNA polymerase δ. PCNA protein levels peak during the S-phase of the cell cycle, at which time it forms a complex with the p21 inhibitor. PCNA is almost undetectable in other phases of the cycle. Because of its unique expression, PCNA has been extensively used in studies associating the prognosis of tumor progression and neoplastic proliferation. Human PCNA has been reported to be 262 amino acids with an apparent molecular weight of 36 kDa.

注意事项：

1. Since applications vary, each investigator should titrate the reagent to obtain optimal results.

2.Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.

3.Store undiluted at 4° C and protected from prolonged exposure to light. Do not freeze.