Hu CD25 PE M-A251 100Tst

产品编号：BD-555432 品牌：BD-Pharmingen 原厂货号：555432
产品分类：抗体 > 一抗 > 染料标记抗体
应用分类：

包装：

100Tst

运保温度:

Store undiluted at 4°C

到货周期：

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描述：

M-A251单克隆抗体特异性地结合被称为低亲和性白细胞介素-2受体α链亚基（IL-2Rα）的55 kDa的I型跨膜糖蛋白。CD25表达与调节性T细胞、活化的淋巴细胞（T和B）和单核细胞。CD25与IL-2Rβ/ CD122和IL-2Rγ/ CD132受体链协同，以形成高亲和力的IL-2R复合物。抗原或有丝分裂的刺激可上调T和B淋巴细胞的CD25表达。刺激淋巴细胞可产生可溶性CD25/ IL-2Rα。

原厂资料：

The M-A251 monoclonal antibody specifically binds to the 55 kDa type I transmembrane glycoprotein known as the low-affinity interleukin-2 receptor alpha chain subunit (IL-2Rα). CD25 is expressed on regulatory T cells and on activated lymphocytes (T and B) and monocytes. It associates with the IL-2Rβ/CD122 and the IL-2Rγ/CD132 receptor chains to form the high-affinity IL-2R complex. CD25 expression on T and B lymphocytes is upregulated by antigenic or mitogenic stimulation. Soluble CD25/IL-2Rα is produced as a consequence of lymphocyte stimulation and is found in biological fluids following inflammatory responses.

注意事项：

1.This reagent has been pre-diluted for use at the recommended Volume per Test. We typically use 1 × 10^6 cells in a 100-μl experimental sample (a test).
2. Since applications vary, each investigator should titrate the reagent to obtain optimal results.

3.Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.