Hu CD19 FITC HIB19 100Tst

• 产品编号：BD-555412      品牌：BD-Pharmingen       原厂货号：555412
• 产品分类：抗体 > 一抗 > 染料标记抗体
• 应用分类：

描述：

HIB19单克隆抗体特异性结合的95 kDa的I型跨膜糖蛋白，该糖蛋白在除了浆细胞以外的B细胞成熟和分化的各个阶段都有表达。 CD19也存在于卵泡树突细胞。T细胞上或正常粒细胞不表达CD19。CD19可调节B细胞的增殖。CD19与补体受体2（CD21）、TAPA-1（CD81）、Leu 13、和/或II类MHC偶联，在B细胞的表面形成信号转导复合物。抗CD19克隆HIB19的抗体可部分阻断CD19与克隆B43（另一CD19单克隆抗体）的结合。
本抗体一般用于流式细胞术检测。

原厂资料：

Reacts with the 95 kDa type I transmembrane glycoprotein expressed during all stages of B-cell differentiation and maturation, except on plasma cells. CD19 is also present on follicular dendritic cells. It is not found on T cells or on normal granulocytes. CD19 plays a role in regulation of B-cell proliferation. It associates with the complement receptor 2 (CD21), TAPA-1 (CD81), Leu 13, and/or MHC class II to form a signal transduction complex on the surface of B cells. Anti-CD19 clone HIB19 partially blocks clone B43, another C19 mAb.
This antibody is routinely tested by flow cytometric analysis.

注意事项：

1.This reagent has been pre-diluted for use at the recommended Volume per Test. We typically use 1 X 10e6 cells in a 100-μl experimental sample (a test).
2. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
3.Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.
4.Source of all serum proteins is from USDA inspected abattoirs located in the United States
5. Store undiluted at 4° C and protected from prolonged exposure to light. Do not freeze.