Hu CD4 FITC RPA-T4 100Tst

• 产品编号：BD-555346      品牌：BD-Pharmingen       原厂货号：555346
• 产品分类：抗体 > 一抗 > 染料标记抗体
• 应用分类：

描述：

RPA-T4克隆与CD4反应。CD4是表达于T辅助/诱导细胞群的一个59 kDa的单链跨膜糖蛋白，是人类免疫缺陷病毒（HIV）的受体。此抗体与CD4抗原的D1结构域（CDR1和CDR3表位）结合，可与大约80％的胸腺细胞和45％的外周血淋巴细胞发生反应。CD4在外周血单核细胞上也有低密度的表达。RPA-T4能够封闭HIV-1、gp120，并且能抑制合胞体的形成。

原厂资料：

The RPA-T4 clone reacts with CD4, a 59 kDa single-chain transmembrane glycoprotein [receptor for human immunodeficiency virus (HIV)] present on T-helper/inducer cell populations. This antibody binds to the D1 domain (CDR1 and CDR3 epitopes) of the CD4 antigen and reacts with approximately 80% of thymocytes and 45% of peripheral blood lymphocytes. CD4 is also present in low density on peripheral blood monocytes. RPA-T4 is capable of blocking HIV-1, gp120, and inhibits syncytium formation.

注意事项：

1.This reagent has been pre-diluted for use at the recommended Volume per Test. We typically use 1 X 10e6 cells in a 100-μl experimental sample (a test).
2. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
3. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.
4.Source of all serum proteins is from USDA inspected abattoirs located in the United States.
5. Store undiluted at 4° C and protected from prolonged exposure to light. Do not freeze.