Ms CD47 Pure miap301 500ug

包装：

500ug

运保温度:

Store undiluted at 4°C.

到货周期：

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描述：

The miap301 antibody reacts with the extracellular domain of CD47, also known as Integrin-Associated Protein (IAP).1 CD47 is a 50-kDa

plasma membrane protein with an extracellular immunoglobulin variable region-like domain, a multiple membrane-spanning segment, and a

short C-terminal cytoplasmic tail. IAP is often physically associated with β3 integrins, and it may act as a transducer element in activation

mediated by these integrins.CD47 is expressed by a wide variety of cell types, including some cells lacking integrins, such as erythrocytes. The

cytoplasmic tail region is expressed as alternatively spliced forms, which are differentially expressed in diverse tissues, suggesting that IAP

may have distinct functions in various tissues. CD47 and its ligand, CD172a, are proposed to mediate bi-directional signaling to modify neural

synaptic activity and regulate the phagocytic activities of macrophages.

注意事项：

1.Since applications vary, each investigator should titrate the reagent to obtain optimal results.

2.Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before

discarding to avoid accumulation of potentially explosive deposits in plumbing.

3.Store undiluted at 4°C.