Rat CD61 FITC F11 500ug

产品编号：BD-554952 品牌：BD-Pharmingen 原厂货号：554952
产品分类：抗体 > 一抗 > 染料标记抗体
应用分类：

包装：

500ug

运保温度:

Store undiluted at 4°C

到货周期：

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描述：

The F11 antibody reacts with the integrin β3 chain (CD61), which associates with the integrin αv chain (CD51), to form the vitronectin

receptor found on endothelial cells, myeloid cells, and osteoclasts, and with the αIIb chain (CD41) on platelets and megakaryocytes. Both

receptors mediate adhesion to fibronectin, fibrinogen, vitronectin, thrombospondin, and von Willebrand factor. F11 mAb has been reported to

block the in vitro attachment of osteoclasts to several ligands. Weak reactivity with human osteoclasts, megakaryocytes, and platelets has also

been observed. Other reported applications include immunoprecipitation, in vitro blocking, and immunohistochemical staining (IHC) of

acetone-fixed frozen and zinc-fixed paraffin-embedded sections. IHC of formalin-fixed paraffin-embedded sections is not recommended

注意事项：

1.Since applications vary, each investigator should titrate the reagent to obtain optimal results.

2.Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.

3.The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.

4.The antibody was conjugated with FITC under optimum conditions, and unreacted FITC was removed.

5.Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.