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Ms CD247 Pure 1zeta3A1 100ug

  • 产品编号:BD-554241      品牌:BD-Pharmingen       原厂货号:554241
  • 产品分类:抗体 > 一抗 > 蛋白特异性一抗
  • 应用分类:
 
包装: 100ug
运保温度: Store undiluted at 4°C.
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描述:

The T-cell receptor (TCR), expressed by thymus-derived lymphocytes, is a multicomponent complex responsible for recognizing antigen in
the context of MHC molecules. Ti is the antigen-specific binding component of the TCR. On the majority of peripheral T lymphocytes, Ti is
present as a disulfide-linked α-β heterodimer. A minor fraction express Ti as a γ-δ heterodimer. The Ti subunits are Ig-like, each containing V
and C regions. Ti is noncovalently associated with an invariant set of molecules referred to as the CD3 subunits. CD3 appears early in
thymocyte differentiation and remains expressed on all mature T lymphocytes. In the mouse, it consists of five chains: γ, δ, ε, ζ, and η. The
relative masses of the mouse CD3 chains are 21, 28, 26, 32, (dimer) and 21 kDa, respectively. Clone 1ζ3A1 recognizes an epitope in the
C-terminus of mouse CD3ζ. A synthetic peptide corresponding to the C-terminus of mouse CD3ζ (BSACDTYDALHMQTLAPR) was used as
immunogen. Hybridomas were derived from Balb/c spleen cells x NS-1.


注意事项:

1.Since applications vary, each investigator should titrate the reagent to obtain optimal results.
2.Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before
discarding to avoid accumulation of potentially explosive deposits in plumbing.
3.Store undiluted at 4°C.


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