Ms CD16/CD32 Pure 2.4G2 500ug

• 产品编号：BD-553142      品牌：BD-Pharmingen       原厂货号：553142
• 产品分类：抗体 > 一抗 > 蛋白特异性一抗
• 应用分类：

描述：

2.4G2抗体特异地与鼠标FcγIII和FcγII受体的胞外域的普通非多态性的表位发生反应。还有报道称，2.4G2抗体通过它的Fc结构域结合FcγI受体（CD64）。 2.4G2单抗块非抗原特异性免疫球蛋白的FcγIII和FcγII，以及可能FcγI的结合，受体在体外和体内。CD16和/或CD32表达于自然杀伤细胞、单核细胞、巨噬细胞、树突细胞（表达水平较低）、枯否细胞、粒细胞、肥大细胞、B淋巴细胞、不成熟的胸腺细胞，及一些活化的成熟的T淋巴细胞。本抗体一般用于流式细胞术分析测试。

原厂资料：

The 2.4G2 antibody reacts specifically with a common nonpolymorphic epitope on the extracellular domains of the mouse FcγIII and FcγII receptors. It has also been reported to bind the FcγI receptor (CD64) via its Fc domain. 2.4G2 mAb blocks non-antigen-specific binding of immunoglobulins to the FcγIII and FcγII, and possibly FcγI, receptors in vitro and in vivo. CD16 and/or CD32 are expressed on natural killer cells, monocytes, macrophages, dendritic cells (at low levels), Kupffer cells, granulocytes, mast cells, B lymphocytes, immature thymocytes, and some activated mature T lymphocytes. This antibody is routinely tested by flow cytometric analysis. Other applications were tested at BD Biosciences Pharmingen during antibody development only or reported in the literature.
 

注意事项：

1.Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.
2. Since applications vary, each investigator should titrate the reagent to obtain optimal results.

3.The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
Store undiluted at 4° C.