LEGEND MAX? Human IL-33 ELISA Kit With Pre-Coated Plates

产品编号：B435907 品牌：Biolegend 原厂货号：435907
产品分类：ELISA及其它免疫分析 > ELISA > ELISA检测试剂盒
应用分类：

包装：

1 Pre-coated Plate

运保温度:

4°C

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其它组分：

Anti-Human IL-33 pre-coated 96-well Strip Microplate【子货号：78593，包装：1 plate，，运保温度：4°C】

Human IL-33 Detection Antibody【子货号：78594，包装：1 bottle，，运保温度：4°C】

Human IL-33 Standard【子货号：78595，包装：1 vial，，运保温度：-70°C】

Avidin-HRP B【子货号：78230，包装：1 bottle，，运保温度：4°C】

Assay Buffer B【子货号：79128，包装：1 bottle，，运保温度：4°C】

Wash Buffer (20X)【子货号：78233，包装：1 bottle，，运保温度：4°C】

Substrate Solution F【子货号：79132，包装：1 bottle，，运保温度：4°C】

Stop Solution【子货号：79133，包装：1 bottle，，运保温度：4°C】

Plate Sealers【子货号：78101，包装：4 sheets，，运保温度：4°C】

描述：

Introduction:

IL-33 belongs to the IL-1 family and is closely related in structure to IL-18 and IL-1b. IL-33 is synthesized as a biologically inactive precursor and is cleaved by the enzyme caspase-1 and secreted as a mature active form. IL-33 stimulates target cells by binding to the IL-1R/TLR superfamily member ST2 and subsequently activates NF-κB and MAPK pathways via identical signaling events to those observed for IL-1b. IL-33 is an inducer of Th2 cytokines such as IL-5 and IL-13. It is also a nuclear factor (NF-HEV) abundantly expressed in high endothelial venules from lymphoid organs that associates with chromatin and exhibits transcriptional regulatory properties.

BioLegend’s LEGEND MAX™ Human IL-33 ELISA kit is a Sandwich Enzyme-Linked Immunosorbent Assay (ELISA) with a 96-well strip plate that is pre-coated with a capture antibody. This kit is specifically designed for the accurate quantitation of human IL-33 from cell culture supernatant, serum, plasma and other biological fluids. It is analytically validated with ready-to-use reagents.

原厂资料：

Introduction:

IL-33 belongs to the IL-1 family and is closely related in structure to IL-18 and IL-1b. IL-33 is synthesized as a biologically inactive precursor and is cleaved by the enzyme caspase-1 and secreted as a mature active form. IL-33 stimulates target cells by binding to the IL-1R/TLR superfamily member ST2 and subsequently activates NF-κB and MAPK pathways via identical signaling events to those observed for IL-1b. IL-33 is an inducer of Th2 cytokines such as IL-5 and IL-13. It is also a nuclear factor (NF-HEV) abundantly expressed in high endothelial venules from lymphoid organs that associates with chromatin and exhibits transcriptional regulatory properties.

BioLegend’s LEGEND MAX™ Human IL-33 ELISA kit is a Sandwich Enzyme-Linked Immunosorbent Assay (ELISA) with a 96-well strip plate that is pre-coated with a capture antibody. This kit is specifically designed for the accurate quantitation of human IL-33 from cell culture supernatant, serum, plasma and other biological fluids. It is analytically validated with ready-to-use reagents.