AHP1907 recognises benzoylmethylecgonine, also known as cocaine or coke, an alkaloid extracted from the leaves of the South American coca plant,Erythroxylon coca. Coca leaves are traditionally chewed or sucked, causing a slow absorption and hence a slow onset of action. Cocaine hydrochloride, however, is a white crystalline powder that may be snorted resulting in very quick absorption and action. It may also be used intravenously or smoked as “crack”. Historically it has had many medicinal uses, including as an analgesic and local anesthetic. Currently, the drug is a controlled substance.
Cocaine stimulates the central nervous system, resulting in increased alertness, euphoria and a sense of confidence and physical strength. It can increase blood pressure, heart rate and body temperature and, once the effects are worn off, may result in anxiety, fatigue and depression. In the body cocaine is rapidly converted to metabolites, mainly benzoylecgonine and ecgonine methyl ester, with benzoylecgonine being the main urinary metabolite.
Application
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visitwww.abdserotec.com/protocols.
Application Name
Yes
No
Not Determined
Suggested Dilution
ELISA
3.5ug/ml
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.
Storage
Store at +4oC or at -20oC if preferred.
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
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