Description: This Human OSM-R Ready-SET-Go! ELISA Set contains the necessary reagents, standards, buffers and diluents for performing quantitative enzyme-linked immunosorbent assays (ELISA). This ELISA set is specifically engineered for accurate and precise measurement of human OSM-R.
Oncostatin M is a pleiotropic cytokine that belongs to the IL-6 group pf cytokines. It is associated with bone formation/destruction, liver development, heamatopoiesis and inflammation. OSM signals through cell surface receptors that contain the protein gp130. Receptors for OSM can be found on a variety of cells from a variety of tissues. In general cells derived from endothelial and tumour origins express high levels of OSM receptors, whereas cells of Haematopoietic origin tend to express lower numbers.
Components
Capture Antibody Concentrate
Detection Antibody Concentrate
Human OSM-R Standard (lyophilized): 40 ng/mL upon reconstitution
Phosphate Buffered Saline Concentrate (PBS)
Assay Buffer A Concentrate (PBS with 1% Tween 20 and 10% BSA)
Sample Diluent Y
pre-titrated Streptavidin-HRP
Tetramethylbenzidine (TMB) Substrate Solution
96 Well Plate included with product Cat. #'s ending in suffixes -22, -76, -86