5602-5008G detects human alpha-lactalbumin, a small Ca2+binding protein that is the predominant protein found in human milk. Alpha-lactalbumin forms the regulatory subunit of the lactose synthase complex, with beta 1,4-galactosyltransferase forming the catalytic component. Lactose synthase catalyzes and regulates the biosynthesis of lactose in the lactating mammary gland.
A folding variant of alpha-lactalbumin called HAMLET (human alpha-lactalbumin made lethal to tumor cells), has been shown to selectively kill tumor cells and control tumor progressionin vivo.
Species Cross-Reactivity
Target Species
Cross Reactivity
Bovine
Weak
Application
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visitwww.abdserotec.com/protocols.
Application Name
Yes
No
Not Determined
Suggested Dilution
ELISA
1/40 - 1/400
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using the appropriate negative/positive controls.
Storage
Store at +4oC or at -20oC if preferred.
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Shelf Life
18 months from date of despatch.
Antiserum Preparation
Antisera to human alpha-lactalbumin were raised by repeated immunisations of sheep with highly purified antigen. Purified IgG prepared by affinity chromatography on Protein G
京公网安备11010802025653 版权所有：北京逸优科技有限公司
