A 13 amino acid synthetic peptide derived from the C-terminus of the mouse Connexin 26 protein. This mouse sequence differs from the rat sequence by a single amino acid and from the human sequence by two (non-consecutive) amino acids.
Conjugate
Unconjugated
Form
Liquid
Concentration
0.25 mg/ml
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.4
Preservative
0.1% sodium azide
Storage Conditions
-20°C
Tested Applications
Dilution *
ELISA (ELISA)
0.1-1.0 ug/ml
Immunocytochemistry (ICC)
1:100-1:500
Immunofluorescence (IF)
1:100-1:500
Immunohistochemistry (Frozen) (IHC (F))
10-20 ug/ml
Immunohistochemistry (Paraffin) (IHC (P))
1:10-1:100
Western Blot (WB)
1-2 ug/ml
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
Gap junctions are conduits that allow the direct cell-to-cell passage of small cytoplasmic molecules, including ions, metabolic intermediates, and second messengers, and thereby mediate intercellular metabolic and electrical communication. Gap junction channels consist of connexin protein subunits, which are encoded by a multigene family. GJBs (gap-junction proteins or connexins) play crucial functional roles associated with these channels. Defects in GJB3 have been linked to erythrokeratodermia variabilis (EKV) is an autosomal dominant genodermatosis characterized by transient figurate red patches or hyperkeratosis. Mutations in GJB2 have also been associated with genetically derived hearing impairments, including autosomal recessive nonsyndromic deafness.
原厂资料：
注意事项：
For Research Use Only. Not for use in diagnostic procedures.
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