Raised against the aa 304-428 of human glucocorticoid receptor.
Conjugate
Unconjugated
Form
Frozen
Concentration
Lot-Specific
Purification
purified
Preservative
<0.1% thimerosal
Storage Conditions
-20° C, Avoid Freeze/Thaw Cycles
Tested Applications
Dilution *
ChIP assay (ChIP)
5 ug
ELISA (ELISA)
0.5 ug/ml
Immunocytochemistry (ICC)
Assay Dependent
Immunofluorescence (IF)
Assay Dependent
Immunohistochemistry (IHC)
2.5 ug/ml
Western Blot (WB)
1.0 ug/ml
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
Background/Target Information
NR3C1 is a receptor for glucocorticoids that can act as both a transcription factor and as a regulator of other transcription factors. This protein can also be found in heteromeric cytoplasmic complexes along with heat shock factors and immunophilins. The protein is typically found in the cytoplasm until it binds a ligand, which induces transport into the nucleus. Mutations in this gene are a cause of glucocorticoid resistance, or cortisol, resistance.
原厂资料：
注意事项：
For Research Use Only. Not for use in diagnostic procedures.
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